Galiellalactone，又称半乳糖内酯、伽利略内酯或肉盘菌内酯，是从子囊菌G.rufa菌株A75-86和A111-95中分离的真菌代谢物，是一种STAT3信号的选择性抑制剂，抑制IL-6介导的STAT3信号，但不影响STAT3的酪氨酸和丝氨酸磷酸化，IC₅₀值为250-500 nM。

参考文献

1.Hellsten R, et, al. Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3. Prostate. 2008 Feb 15; 68(3): 269-80.

2.Doncow DN, et, al. Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cells. J Biol Chem. 2014 Jun 6; 289(23): 15969-78.

3.Weidler M, et, al. Inhibition of interleukin-6 signaling by galiellalactone. FEBS Lett. 2000 Oct 27; 484(1): 1-6.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃避光保存，避免反复冻融。