EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

推荐稀释比 WB:1/1000-1/5000; IHC:P:1/100-1/200; ICC/IF:1/200-1/500; FC:1/100-1/1000; IP:1/20-1/50

Immunocytochemistry analysis of EGFR (green) in 3T3 using EGFR antibody,and DAPI(blue).

Western blot analysis of EGFR in Hela lysates using EGFR antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using EGFR antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.