This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

推荐稀释比 WB:1/500-1/1000; IHC:P:1/1000-1/5000; ICC/IF:1/50-1/100; IP:1/20-1/50

Western blot analysis of EpCAM in rat colon, mouse colon lysates using EpCAM antibody.

Western blot analysis of EpCAM in MCF-7, HCT116, T47D, Hela lysates using EpCAM antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using EpCAM antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of EpCAM (green) in MCF-7 using EpCAM antibody,and DAPI(blue).

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.