The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD) . Targeting this pathway has opened new avenues for therapeutic intervention.

高活性、高纯度、低内毒素、高批间一致性

ELISA Data 1:Immobilized Cynomolgus IL-23 alpha&IL-12 beta, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human IL-23R, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA .

SPR Data: Human IL-23R, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 4.05 nM as determined in SPR assay .

-25~-15℃保存，收到货之日起，有效期1年。复溶后， -85~-65℃保存，3个月有效期。避免反复冻融。