Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq, Jul

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Human embryonic brain cortex tissue using Kallikrein 8 antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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