CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Immunocytochemistry analysis of CD146 (green) in Hela using CD146 antibody,and DAPI(blue).

Western blot analysis of CD146 in C6, Hela lysates using CD146 antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon cancer tissue using CD146 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.