LAMP1 and LAMP2 (lysosome-associated membrane protein 1 and 2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplam and contains a tyrosine sorting motif which targets LAMP to lysosomal membranes.

Western

Western blot analysis of LAMP1 in various cell lines lysates using LAMP1 antibody.

Immunofluorescence

Immunofluorescence analysis of LAMP1 in C6 using LAMP1 antibody,and DAPI (blue).

Immunofluorescence

Immunofluorescence analysis of LAMP1 in NIH/3T3 cells using LAMP1 antibody,and DAPI (blue).