ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACCα (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACCβ (ACC2) is the major isoform in skeletal muscle and heart.

Western

Western blot analysis of Acetyl Coenzyme A Carboxylase in A431 lysates using Acetyl Coenzyme A Carboxylase antibody.

Western

Western blot analysis of Acetyl Coenzyme A Carboxylase in C2C12 lysates using Acetyl Coenzyme A Carboxylase antibody.

Western

Western blot analysis of AcetylCoA Carboxylase in A431 lysates using Acetyl Coenzyme A Carboxylase antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human kidney using AcetylCoA Carboxylase antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.