This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Western

Western blot analysis of Progesterone Receptor in T47D (1), and C2C12 (2) cell lysate using Progesterone Receptor antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues using Progesterone Receptor antibody.

Flow

Flow Cytometry analysis of Hela cells using Progesterone Receptor antibody (green) and negative control (red).