Purity:SDS-PAGE
Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
Purity:SEC-HPLC
The purity of Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) is more than 95%, determined by SEC-HPLC.
Bioactivity:ELISA
Immobilized human HER2, His at 2 ug/mL can bind Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab), EC50=0.005735 ug/mL.
Bioactivity:FACS
BT474 cells were stained with Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.3024 ug/mL.
Research in vivo
Trastuzumab inhibited the tumor growth of BT474 on NCG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 88.5% at 10 mpk at D35.
-25~-15℃保存,有效期1年。