LDN-193189 (LDN193189, DM3189, DM-3189) 2HCl,是一种选择性BMP信号抑制剂,抑制ALK1/2/3/6,IC50分别为0.8 nM、0.8 nM、5.3 nM和16.7 nM。LDN-193189已被用于研究进行性骨化性纤维发育不良的发病机制、先天性骨化障碍和骨形成在前列腺肿瘤骨转移中的作用。
参考文献
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冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。