Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

推荐稀释比 WB:1/1000-1/2000; IF:1/50-1/200; FC:1/50-1/100; IP:1/50

Western blot analysis of p53 in (1) A431 ; (2) HEK293 lysates using p53 antibody.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.